Wednesday, August 10, 2011

Breast Cancer News (8/10): Exercise, Avastin and Soy

In today's breast cancer news update, we'll share the latest media headlines on exercise, Avastin and soy. As always, links to the news stories discussed below may be found on the treatment pages of the website.

The New York Times: "The Benefits of Exercise After Cancer"

Yesterday, The New York Times shared a recent report on the benefits of exercise during and after cancer treatment. In the report, "The importance of physical activity for people living with and beyond cancer:
A concise evidence review," Macmillan Cancer Support (UK) reviewed 60 studies on exercise during and after cancer treatment. Exercise was found to reduce the risk of breast-cancer mortality and recurrence. It also improved physical function, fatigue, well-being, body composition and bone health. For women with advanced breast cancer receiving chemotherapy, exercise affected quality of life and fatigue. The Macmillan Cancer Support webpage is full of additional information on physical activity for cancer patients and healthcare providers.

Bloomberg: "Roche Seeks ‘Middle Ground’ in U.S. Appeal of Avastin Breast Cancer Ruling"

The Avastin (bevacizumab) regulatory saga continues. According to a story in Bloomberg, Roche has appealed the recent FDA withdrawal of approval of Avastin for metastatic breast cancer with a "middle ground proposal." Roche asked the FDA to allow patients with advanced, aggressive cancer with few treatment options to use Avastin with Taxol (paclitaxel). The proposal includes an offer to provide doctors with a "risk-evaluation strategy" and additional information on Avastin effectiveness and risks. Roche also plans a 480 patient follow-up trial. Trial failure would trigger an "immediate voluntary withdrawal of Avastin for breast cancer." The trial is to include a test of a protein biomarker (VEGF-A) to identify patients who may benefit from Avastin.

The Los Angeles Times: "Study indicates soy won't fight bone loss after menopause"

After breast cancer treatment, some women turn to natural remedies, such as soy, for menopausal symptoms such as hot flashes and bone loss. According to a story in yesterday's Los Angeles Times, a recent study in the Archives of Internal Medicine has found that soy tablets do not reduce bone loss in post-menopausal women. Further, the women who took soy experienced more hot flashes and constipation. The women in the study were not breast cancer survivors, but the effects of soy on menopausal symptoms should still apply.

Please check back tomorrow for more breast cancer news and research updates from

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