Monday, May 23, 2011

The Breast Cancer News Update: May 23

All of today's breast cancer news involves early research. Although these discoveries are not yet available in clinical practice, it's interesting to see what's coming down the pike.

Link between obesity gene and breast cancer risk

Chicago researchers discovered a connection between obesity and breast cancer risk. In the study, people who possessed a variant in the fat mass and obesity associated gene (FTO) had a 30% greater risk of developing breast cancer. Everyone carries the FTO gene, but only 18% have the variant. Testing is not currently available.

Biomarker predicts Taxane-induced neuropathy

Researchers in Indiana identified a biomarker which predicts who is at risk for neuropathy, or nerve pain, numbness or tingling, from taxane chemotherapy, such as Taxol (paclitaxel). Again, a test is not currently available and further research is planned.

Protein is involved in development of tamoxifen resistance

UK researchers identified a protein which is involved in the development of tamoxifen resistance. In animal and cell studies, blocking the production of the protein made tamoxifen resistant cancer cells more responsive to tamoxifen. Scientists are now looking for drugs to block the effects of the protein.

At, we'll continue to follow these and other early breast cancer research developments. When something becomes clinically relevant, or an option for a patient today, even if off-label or in clinical trial, we add it to our database. All clinically relevant test and treatment options can be found on our website.

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